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Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery
BACKGROUND: Extant life depends greatly on the binding of small molecules (such as ligands) with macromolecules (such as proteins), and one ligand can bind multiple proteins. However, little is known about the global patterns of ligand-protein mapping. RESULTS: By examining 2,186 well-defined small-...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375006/ https://ncbi.nlm.nih.gov/pubmed/17727706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-8-r176 |
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