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Structure-Based DNA-Targeting Strategies with Small Molecule Ligands for Drug Discovery

Nucleic acids are the molecular targets of many clinical anticancer drugs. However, compared with proteins, nucleic acids have traditionally attracted much less attention as drug targets in structure-based drug design, partially because limited structural information of nucleic acids complexed with...

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Détails bibliographiques
Auteurs principaux: Sheng, Jia, Gan, Jianhua, Huang, Zhen
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954796/
https://ncbi.nlm.nih.gov/pubmed/23633219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21278
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