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Structure-Based DNA-Targeting Strategies with Small Molecule Ligands for Drug Discovery

Nucleic acids are the molecular targets of many clinical anticancer drugs. However, compared with proteins, nucleic acids have traditionally attracted much less attention as drug targets in structure-based drug design, partially because limited structural information of nucleic acids complexed with...

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Detalhes bibliográficos
Main Authors: Sheng, Jia, Gan, Jianhua, Huang, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954796/
https://ncbi.nlm.nih.gov/pubmed/23633219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21278
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