Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin

The human pathology Wilson disease (WD) is characterized by toxic copper (Cu) accumulation in brain and liver, resulting in, among other indications, mitochondrial dysfunction and apoptosis of hepatocytes. In an effort to identify novel compounds that can alleviate Cu-induced toxicity, we screened t...

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Detalhes bibliográficos
Publicado no:Microb Cell
Main Authors: Spincemaille, Pieter, Chandhok, Gursimran, Zibert, Andree, Schmidt, Hartmut, Verbeek, Jef, Chaltin, Patrick, Cammue, Bruno P., Cassiman, David, Thevissen, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2014
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349125/
https://ncbi.nlm.nih.gov/pubmed/28357214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2014.11.175
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