Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin

The human pathology Wilson disease (WD) is characterized by toxic copper (Cu) accumulation in brain and liver, resulting in, among other indications, mitochondrial dysfunction and apoptosis of hepatocytes. In an effort to identify novel compounds that can alleviate Cu-induced toxicity, we screened t...

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Détails bibliographiques
Publié dans:Microb Cell
Auteurs principaux: Spincemaille, Pieter, Chandhok, Gursimran, Zibert, Andree, Schmidt, Hartmut, Verbeek, Jef, Chaltin, Patrick, Cammue, Bruno P., Cassiman, David, Thevissen, Karin
Format: Artigo
Langue:Inglês
Publié: Shared Science Publishers OG 2014
Sujets:
Microbiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349125/
https://ncbi.nlm.nih.gov/pubmed/28357214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2014.11.175
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