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Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin

The human pathology Wilson disease (WD) is characterized by toxic copper (Cu) accumulation in brain and liver, resulting in, among other indications, mitochondrial dysfunction and apoptosis of hepatocytes. In an effort to identify novel compounds that can alleviate Cu-induced toxicity, we screened t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Microb Cell
Prif Awduron: Spincemaille, Pieter, Chandhok, Gursimran, Zibert, Andree, Schmidt, Hartmut, Verbeek, Jef, Chaltin, Patrick, Cammue, Bruno P., Cassiman, David, Thevissen, Karin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shared Science Publishers OG 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349125/
https://ncbi.nlm.nih.gov/pubmed/28357214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2014.11.175
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