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Protein misfolding in neurodegenerative diseases: implications and strategies
A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity and contribute to cellular proteostatic collapse. Therapeutic options are currently being explored that target different steps in the production and processing of proteins im...
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| Опубликовано в: : | Transl Neurodegener |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5348787/ https://ncbi.nlm.nih.gov/pubmed/28293421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-017-0077-5 |
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