Protein misfolding in neurodegenerative diseases: implications and strategies

A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity and contribute to cellular proteostatic collapse. Therapeutic options are currently being explored that target different steps in the production and processing of proteins im...

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Sweeney, Patrick, Park, Hyunsun, Baumann, Marc, Dunlop, John, Frydman, Judith, Kopito, Ron, McCampbell, Alexander, Leblanc, Gabrielle, Venkateswaran, Anjli, Nurmi, Antti, Hodgson, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348787/
https://ncbi.nlm.nih.gov/pubmed/28293421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-017-0077-5
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