Protein misfolding in neurodegenerative diseases: implications and strategies

A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity and contribute to cellular proteostatic collapse. Therapeutic options are currently being explored that target different steps in the production and processing of proteins im...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Transl Neurodegener
Egile Nagusiak: Sweeney, Patrick, Park, Hyunsun, Baumann, Marc, Dunlop, John, Frydman, Judith, Kopito, Ron, McCampbell, Alexander, Leblanc, Gabrielle, Venkateswaran, Anjli, Nurmi, Antti, Hodgson, Robert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Review
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348787/
https://ncbi.nlm.nih.gov/pubmed/28293421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-017-0077-5
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