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Activation of peroxisome proliferator-activated receptor γ inhibits vascular calcification by upregulating Klotho

Cardiovascular diseases are common in patients with chronic kidney disease. One of the key symptoms is the calcification of the vascular smooth muscle cells (VSMCs), which is induced by dysregulated mineral metabolism with high circulating levels of inorganic phosphate (Pi) and calcium. Klotho, whic...

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Опубликовано в: :Exp Ther Med
Главные авторы: Cheng, Lijuan, Zhang, Lei, Yang, Jun, Hao, Lirong
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348673/
https://ncbi.nlm.nih.gov/pubmed/28352317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3996
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