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Activation of peroxisome proliferator-activated receptor γ inhibits vascular calcification by upregulating Klotho

Cardiovascular diseases are common in patients with chronic kidney disease. One of the key symptoms is the calcification of the vascular smooth muscle cells (VSMCs), which is induced by dysregulated mineral metabolism with high circulating levels of inorganic phosphate (Pi) and calcium. Klotho, whic...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Cheng, Lijuan, Zhang, Lei, Yang, Jun, Hao, Lirong
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348673/
https://ncbi.nlm.nih.gov/pubmed/28352317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3996
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