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Activation of peroxisome proliferator-activated receptor γ inhibits vascular calcification by upregulating Klotho

Cardiovascular diseases are common in patients with chronic kidney disease. One of the key symptoms is the calcification of the vascular smooth muscle cells (VSMCs), which is induced by dysregulated mineral metabolism with high circulating levels of inorganic phosphate (Pi) and calcium. Klotho, whic...

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Bibliographische Detailangaben
Veröffentlicht in:Exp Ther Med
Hauptverfasser: Cheng, Lijuan, Zhang, Lei, Yang, Jun, Hao, Lirong
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348673/
https://ncbi.nlm.nih.gov/pubmed/28352317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3996
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