Gambogic acid potentiates the chemosensitivity of colorectal cancer cells to 5-fluorouracil by inhibiting proliferation and inducing apoptosis

Chemotherapy using 5-fluorouracil (5-FU) for colorectal cancer (CRC) has low specificity and response rates, leading to severe side effects. Gambogic acid (GA), a traditional Chinese medicine, has multi-targeted anticancer effects, including growth inhibition and apoptosis induction. However, it is...

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Udgivet i:Exp Ther Med
Main Authors: Wei, Jianchang, Yang, Ping, Li, Wanglin, He, Feng, Zeng, Shanqi, Zhang, Tong, Zhong, Junbin, Huang, Di, Chen, Zhuanpeng, Wang, Chengxing, Chen, Huacui, Hu, He, Cao, Jie
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348657/
https://ncbi.nlm.nih.gov/pubmed/28352348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4021
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