Gambogic acid reverses oxaliplatin resistance in colorectal cancer by increasing intracellular platinum levels

Resistance to oxaliplatin (L-OHP) is a major obstacle to successful chemotherapy in colorectal cancer (CRC). In the present study, the ability of gambogic acid (GA) to reverse L-OHP resistance in CRC LoVo cells was investigated. L-OHP-resistant LoVo/L-OHP cells were established by exposing them to i...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Wang, Qiang, Wei, Jianchang, Wang, Chengxing, Zhang, Tong, Huang, Di, Wei, Fang, He, Feng, Cai, Wensong, Yang, Ping, Zeng, Shanqi, Li, Wanglin, Cao, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036459/
https://ncbi.nlm.nih.gov/pubmed/30008940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8916
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