Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C

BACKGROUND: Human natural killer (NK) cell activity is regulated by a family of killer cell immunoglobulin-like receptors (KIRs) that bind human leukocyte antigen (HLA) class I. Combinations of KIR and HLA genotypes are associated with disease, including susceptibility to viral infection and disorde...

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Pubblicato in:Front Immunol
Autori principali: Sim, Malcolm J. W., Malaker, Stacy A., Khan, Ayesha, Stowell, Janet M., Shabanowitz, Jeffrey, Peterson, Mary E., Rajagopalan, Sumati, Hunt, Donald F., Altmann, Daniel M., Long, Eric O., Boyton, Rosemary J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348643/
https://ncbi.nlm.nih.gov/pubmed/28352266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00193
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