Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C

BACKGROUND: Human natural killer (NK) cell activity is regulated by a family of killer cell immunoglobulin-like receptors (KIRs) that bind human leukocyte antigen (HLA) class I. Combinations of KIR and HLA genotypes are associated with disease, including susceptibility to viral infection and disorde...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Sim, Malcolm J. W., Malaker, Stacy A., Khan, Ayesha, Stowell, Janet M., Shabanowitz, Jeffrey, Peterson, Mary E., Rajagopalan, Sumati, Hunt, Donald F., Altmann, Daniel M., Long, Eric O., Boyton, Rosemary J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348643/
https://ncbi.nlm.nih.gov/pubmed/28352266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00193
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