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A Structure-Based Mechanism for Oxidative Decarboxylation Reactions Mediated by Amino Acids and Heme Propionates in Coproheme Decarboxylase (HemQ)

Coproheme decarboxylase catalyzes two sequential oxidative decarboxylations with H(2)O(2) as the oxidant, coproheme III as substrate and cofactor, and heme b as the product. Each reaction breaks a C-C bond and results in net loss of hydride, via steps that are not clear. Solution and solid-state str...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Celis, Arianna I., Gauss, George H., Streit, Bennett R., Shisler, Krista, Moraski, Garrett C., Rodgers, Kenton R., Lukat-Rodgers, Gudrun S., Peters, John W., DuBois, Jennifer L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348300/
https://ncbi.nlm.nih.gov/pubmed/27936663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11324
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