Depletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation

Altered expression of NEAT1, the architectural long non-coding RNA (lncRNA) of nuclear paraspeckles, has been reported during tumorigenesis, as well as under various cellular stress conditions. Here we report that the depletion of NEAT1 lncRNA alleviates nucleolar stress during RNAP I inhibition thr...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Shen, Wen, Liang, Xue-hai, Sun, Hong, De Hoyos, Cheryl L., Crooke, Stanley T.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348036/
https://ncbi.nlm.nih.gov/pubmed/28288210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173494
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