Depletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation

Altered expression of NEAT1, the architectural long non-coding RNA (lncRNA) of nuclear paraspeckles, has been reported during tumorigenesis, as well as under various cellular stress conditions. Here we report that the depletion of NEAT1 lncRNA alleviates nucleolar stress during RNAP I inhibition thr...

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Foilsithe in:PLoS One
Main Authors: Shen, Wen, Liang, Xue-hai, Sun, Hong, De Hoyos, Cheryl L., Crooke, Stanley T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348036/
https://ncbi.nlm.nih.gov/pubmed/28288210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173494
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