Stimulation of allergen-loaded macrophages by TLR9-ligand potentiates IL-10-mediated suppression of allergic airway inflammation in mice

BACKGROUND: Previously, we demonstrated that OVA-loaded macrophages (OVA-Mφ) partially suppress OVA-induced airway manifestations of asthma in BALB/c mice. In vitro studies showed that OVA-Mφ start to produce IL-10 upon interaction with allergen-specific T cells, which might mediate their immunosupp...

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Hauptverfasser: Vissers, Joost LM, van Esch, Betty CAM, Jeurink, Prescilla V, Hofman, Gerard A, van Oosterhout, Antoon JM
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2004
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC534803/
https://ncbi.nlm.nih.gov/pubmed/15538945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-5-21
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