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TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon

BACKGROUND: Toll-interacting protein is a negative regulator in the TLR signaling cascade, particularly by impeding the TLR2 and, TLR4 pathway. Recently, TOLLIP was shown to regulate human TLR signaling pathways. Two common TOLLIP polymorphisms (rs5743899 and rs3750920) were reported to be influenci...

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Publicat a:Malar J
Autors principals: Brasil, Larissa W., Barbosa, Laila R. A., de Araujo, Felipe J., da Costa, Allyson G., da Silva, Luan D. O., Pinheiro, Suzana K., de Almeida, Anne C. G., Kuhn, Andrea, Vitor-Silva, Sheila, de Melo, Gisely C., Monteiro, Wuelton M., de Lacerda, Marcus V. G., Ramasawmy, Rajendranath
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347824/
https://ncbi.nlm.nih.gov/pubmed/28288644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1754-7
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