A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress

Chondrosarcoma is one of the bone tumor with high mortality in respond to poor radiation and chemotherapy treatment. Here, we analyze the antitumor activity of a novel benzofuran derivative, 2-amino-3-(2-chlorophenyl)-6-(4-dimethylaminophenyl)benzofuran-4-yl acetate (ACDB), in human chondrosarcoma c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Su, Chen-Ming, Chen, Chien-Yu, Lu, Tingting, Sun, Yi, Li, Weimin, Huang, Yuan-Li, Tsai, Chun-Hao, Chang, Chih-Shiang, Tang, Chih-Hsin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347786/
https://ncbi.nlm.nih.gov/pubmed/27835579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13171
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