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BL-038, a Benzofuran Derivative, Induces Cell Apoptosis in Human Chondrosarcoma Cells through Reactive Oxygen Species/Mitochondrial Dysfunction and the Caspases Dependent Pathway

Chondrosarcoma is a highly malignant cartilage-forming bone tumor that has the capacity to invade locally and cause distant metastasis. Moreover, chondrosarcoma is intrinsically resistant to conventional chemotherapy or radiotherapy. The novel benzofuran derivative, BL-038 (2-amino-3-(2,6-dichloroph...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Liu, Ju-Fang, Chen, Chien-Yu, Chen, Hsien-Te, Chang, Chih-Shiang, Tang, Chih-Hsin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037769/
https://ncbi.nlm.nih.gov/pubmed/27618007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17091491
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