A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress

Chondrosarcoma is one of the bone tumor with high mortality in respond to poor radiation and chemotherapy treatment. Here, we analyze the antitumor activity of a novel benzofuran derivative, 2-amino-3-(2-chlorophenyl)-6-(4-dimethylaminophenyl)benzofuran-4-yl acetate (ACDB), in human chondrosarcoma c...

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Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Su, Chen-Ming, Chen, Chien-Yu, Lu, Tingting, Sun, Yi, Li, Weimin, Huang, Yuan-Li, Tsai, Chun-Hao, Chang, Chih-Shiang, Tang, Chih-Hsin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347786/
https://ncbi.nlm.nih.gov/pubmed/27835579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13171
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