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Extending enzyme molecular recognition with an expanded amino acid alphabet

Natural enzymes are constructed from the 20 proteogenic amino acids, which may then require posttranslational modification or the recruitment of coenzymes or metal ions to achieve catalytic function. Here, we demonstrate that expansion of the alphabet of amino acids can also enable the properties of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Windle, Claire L., Simmons, Katie J., Ault, James R., Trinh, Chi H., Nelson, Adam, Pearson, Arwen R., Berry, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347630/
https://ncbi.nlm.nih.gov/pubmed/28196894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616816114
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