Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

Opioids are first-line drugs for moderate to severe acute pain and cancer pain. However, these medications are associated with severe side effects, and whether they are efficacious in treatment of chronic nonmalignant pain remains controversial. Medications that act through alternative molecular mec...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Romero, Haylie K., Christensen, Sean B., Di Cesare Mannelli, Lorenzo, Gajewiak, Joanna, Ramachandra, Renuka, Elmslie, Keith S., Vetter, Douglas E., Ghelardini, Carla, Iadonato, Shawn P., Mercado, Jose L., Olivera, Baldomera M., McIntosh, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347537/
https://ncbi.nlm.nih.gov/pubmed/28223528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621433114
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