Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

Opioids are first-line drugs for moderate to severe acute pain and cancer pain. However, these medications are associated with severe side effects, and whether they are efficacious in treatment of chronic nonmalignant pain remains controversial. Medications that act through alternative molecular mec...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Romero, Haylie K., Christensen, Sean B., Di Cesare Mannelli, Lorenzo, Gajewiak, Joanna, Ramachandra, Renuka, Elmslie, Keith S., Vetter, Douglas E., Ghelardini, Carla, Iadonato, Shawn P., Mercado, Jose L., Olivera, Baldomera M., McIntosh, J. Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2017
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347537/
https://ncbi.nlm.nih.gov/pubmed/28223528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621433114
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