α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors

α6-containing (α6*) nicotinic acetylcholine receptors (nAChRs) are expressed throughout the periphery and the central nervous system and constitute putative therapeutic targets in pain, addiction and movement disorders. The α6β2* nAChRs are relatively well studied, in part due to the availability of...

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Publicado no:Neuropharmacology
Main Authors: van Hout, Marloes, Valdes, Amanda, Christensen, Sean B., Tran, Phuong T., Watkins, Maren, Gajewiak, Joanna, Jensen, Anders A., Olivera, Baldomero M., McIntosh, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693646/
https://ncbi.nlm.nih.gov/pubmed/31255696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2019.107691
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