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Sarcolipin retention in the endoplasmic reticulum depends on its C-terminal RSYQY sequence and its interaction with sarco(endo)plasmic Ca(2)+-ATPases

Sarcolipin (SLN) and phospholamban (PLN) are effective inhibitors of the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA). These homologous proteins differ at their N and C termini: the C-terminal Met-Leu-Leu in PLN is replaced by Arg-Ser-Tyr-Gln-Tyr in SLN. The role of the C-terminal sequence of...

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Autors principals: Gramolini, Anthony O., Kislinger, Thomas, Asahi, Michio, Li, Wenping, Emili, Andrew, MacLennan, David H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC534750/
https://ncbi.nlm.nih.gov/pubmed/15556994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407815101
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