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Drug Interactions With the Ca2+-ATPase From Sarco(Endo)Plasmic Reticulum (SERCA)

The sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) is an intracellular membrane transporter that utilizes the free energy provided by ATP hydrolysis for active transport of Ca2+ ions from the cytoplasm to the lumen of sarco(endo)plasmic reticulum. SERCA plays a fundamental role for cell calcium ho...

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Autors principals: Francesco Tadini-Buoninsegni, Serena Smeazzetto, Roberta Gualdani, Maria Rosa Moncelli
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018-04-01
Col·lecció:Frontiers in Molecular Biosciences
Matèries:
anticancer drug
antimalarial agent
drug-protein interaction
sarco(endo)plasmic reticulum Ca2+-ATPase
SERCA activator
SERCA inhibitor
Accés en línia:http://journal.frontiersin.org/article/10.3389/fmolb.2018.00036/full
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