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Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel
Entry of the enzymatic components of anthrax toxin [lethal factor (LF) and edema factor] into the cytosol of mammalian cells depends on the ability of the activated protective antigen (PA(63)) component to form a channel (pore) in the membrane of an acidic intracellular compartment. To investigate t...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534726/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15548616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0405754101 |
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