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Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel

Entry of the enzymatic components of anthrax toxin [lethal factor (LF) and edema factor] into the cytosol of mammalian cells depends on the ability of the activated protective antigen (PA(63)) component to form a channel (pore) in the membrane of an acidic intracellular compartment. To investigate t...

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Detalhes bibliográficos
Main Authors: Zhang, Sen, Finkelstein, Alan, Collier, R. John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC534726/
https://ncbi.nlm.nih.gov/pubmed/15548616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405754101
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