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Linkage analysis of ordinal traits for pedigree data

Linkage analysis is used routinely to map genes for human diseases and conditions. However, the existing linkage-analysis methods require that the diseases or conditions either be dichotomized or measured by a quantitative trait, such as blood pressure for hypertension. In the latter case, normality...

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Библиографические подробности
Главные авторы: Feng, Rui, Leckman, James F., Zhang, Heping
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC534720/
https://ncbi.nlm.nih.gov/pubmed/15548606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404623101
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