Killing of Staphylococcus aureus and Salmonella enteritidis and neutralization of lipopolysaccharide by 17-residue bovine lactoferricins: improved activity of Trp/Ala-containing molecules

Bovine lactoferricin (LfcinB) has potent antibacterial, antifungal and antiparasitic activities but is also hemolytic. Our objective was to identify LfcinB17-31 derivatives with reduced hemolysis and improved antimicrobial activity via substituting Cys3, Arg4, Gln7, Met10, and Gly14 with more hydrop...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Hao, Ya, Yang, Na, Wang, Xiumin, Teng, Da, Mao, Ruoyu, Wang, Xiao, Li, Zhanzhan, Wang, Jianhua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347165/
https://ncbi.nlm.nih.gov/pubmed/28287172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44278
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