Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli

Pathogenic Escherichia coli can cause fatal diarrheal diseases in both animals and humans. However, no antibiotics or antimicrobial peptides (AMPs) can adequately kill resistant bacteria and clear bacterial endotoxin, lipopolysaccharide (LPS) which leads to inflammation and sepsis. Here, the LPS-tar...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Wang, Zhenlong, Liu, Xuehui, Da Teng, Mao, Ruoyu, Hao, Ya, Yang, Na, Wang, Xiao, Li, Zhanzhan, Wang, Xiumin, Wang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978316/
https://ncbi.nlm.nih.gov/pubmed/31974490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0761-3
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