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AKT1 and AKT2 isoforms play distinct roles during breast cancer progression through the regulation of specific downstream proteins

The purpose of this study was to elucidate the mechanisms associated with the specific effects of AKT1 and AKT2 isoforms in breast cancer progression. We modulated the abundance of specific AKT isoforms in IBH-6 and T47D human breast cancer cell lines and showed that AKT1 promoted cell proliferation...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Riggio, Marina, Perrone, María C., Polo, María L., Rodriguez, María J., May, María, Abba, Martín, Lanari, Claudia, Novaro, Virginia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347151/
https://ncbi.nlm.nih.gov/pubmed/28287129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44244
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