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Development of [(18)F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging

[Image: see text] Dysregulation of glycogen synthase kinase-3β (GSK-3β) is implicated in the pathogenesis of neurodegenerative and psychiatric disorders. Thus, development of GSK-3β radiotracers for positron emission tomography (PET) imaging is of paramount importance, because such a noninvasive ima...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Hu, Kongzhen, Patnaik, Debasis, Collier, Thomas Lee, Lee, Katarzyna N., Gao, Han, Swoyer, Matthew R., Rotstein, Benjamin H., Krishnan, Hema S., Liang, Steven H., Wang, Jin, Yan, Zhiqiang, Hooker, Jacob M., Vasdev, Neil, Haggarty, Stephen J., Ngai, Ming-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346984/
https://ncbi.nlm.nih.gov/pubmed/28337318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00405
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