Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles

Colon cancer is one of the leading causes of cancer-related death worldwide and the therapy with 5-fluorouracil (5-FU) is mainly limited due to resistance. Recently, we have demonstrated that nucleolar stress upon 5-FU treatment leads to the activation of ribosome-free rpL3 (L3) as proapoptotic fact...

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Publicat a:Oncotarget
Autors principals: Russo, Annapina, Maiolino, Sara, Pagliara, Valentina, Ungaro, Francesca, Tatangelo, Fabiana, Leone, Alessandra, Scalia, Giulia, Budillon, Alfredo, Quaglia, Fabiana, Russo, Giulia
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346744/
https://ncbi.nlm.nih.gov/pubmed/27835895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13216
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