Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53

Many chemotherapeutic drugs cause nucleolar stress and p53-independent pathways mediating the nucleolar stress response are emerging. Here, we demonstrate that ribosomal stress induced by Actinomycin D (Act D) is associated to the up-regulation of ribosomal protein L3 (rpL3) and its accumulation as...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Russo, Annapina, Pagliara, Valentina, Albano, Francesco, Esposito, Davide, Sagar, Vinay, Loreni, Fabrizio, Irace, Carlo, Santamaria, Rita, Russo, Giulia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825706/
https://ncbi.nlm.nih.gov/pubmed/26636733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1120926
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