Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes

Anaplastic large cell lymphomas (ALCL) represent a peripheral T-cell lymphoma subgroup, stratified based on the presence or absence of anaplastic lymphoma kinase (ALK) chimeras. Although ALK-positive ALCLs have a more favorable outcome than ALK-negative ALCL, refractory and/or relapsed forms are com...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Boi, Michela, Todaro, Maria, Vurchio, Valentina, Yang, Shao Ning, Moon, John, Kwee, Ivo, Rinaldi, Andrea, Pan, Heng, Crescenzo, Ramona, Cheng, Mangeng, Cerchietti, Leandro, Elemento, Olivier, Riveiro, Maria E., Cvitkovic, Esteban, Bertoni, Francesco, Inghirami, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346742/
https://ncbi.nlm.nih.gov/pubmed/27793034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12876
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