GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity

Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous. To investigate the role for EGFRvIII activati...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Lindberg, Olle R., McKinney, Andrew, Engler, Jane R., Koshkakaryan, Gayane, Gong, Henry, Robinson, Aaron E., Ewald, Andrew J., Huillard, Emmanuelle, James, C. David, Molinaro, Annette M., Shieh, Joseph T., Phillips, Joanna J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346701/
https://ncbi.nlm.nih.gov/pubmed/27738329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12600
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