GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity

Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous. To investigate the role for EGFRvIII activati...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lindberg, Olle R., McKinney, Andrew, Engler, Jane R., Koshkakaryan, Gayane, Gong, Henry, Robinson, Aaron E., Ewald, Andrew J., Huillard, Emmanuelle, James, C. David, Molinaro, Annette M., Shieh, Joseph T., Phillips, Joanna J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346701/
https://ncbi.nlm.nih.gov/pubmed/27738329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12600
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