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AI-20 MECHANISMS OF RESISTANCE TO EGFR INHIBITION ASSOCIATED WITH AN INVASIVE PHENOTYPE

To date, strategies targeting epidermal growth factor receptor (EGFR) signaling in glioblastoma (GBM) have had disappointing results in the clinic. One mechanism of resistance is thought to be the diversity of signaling pathways driving proliferation in GBM; however, given the heterogeneity of GBM,...

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Detalhes bibliográficos
Main Authors: McKinney, Andrew, Engler, Jane, Phillips, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217859/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou238.20
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