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AI-20 MECHANISMS OF RESISTANCE TO EGFR INHIBITION ASSOCIATED WITH AN INVASIVE PHENOTYPE

To date, strategies targeting epidermal growth factor receptor (EGFR) signaling in glioblastoma (GBM) have had disappointing results in the clinic. One mechanism of resistance is thought to be the diversity of signaling pathways driving proliferation in GBM; however, given the heterogeneity of GBM,...

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Hlavní autoři: McKinney, Andrew, Engler, Jane, Phillips, Joanna
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217859/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou238.20
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