Autophagy negatively regulates tumor cell proliferation through phosphorylation dependent degradation of the Notch1 intracellular domain

Autophagy is a highly conserved mechanism that degrades long-lived proteins and dysfunctional organelles, and contributes to cell fate. In this study, autophagy attenuates Notch1 signaling by degrading the Notch1 intracellular domain (Notch1-IC). Nutrient-deprivation promotes Notch1-IC phosphorylati...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Ahn, Ji-Seon, Ann, Eun-Jung, Kim, Mi-Yeon, Yoon, Ji-Hye, Lee, Hye-Jin, Jo, Eun-Hye, Lee, Keesook, Lee, Ji Shin, Park, Hee-Sae
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346697/
https://ncbi.nlm.nih.gov/pubmed/27806347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12986
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars