Wnt5a Controls Notch1 Signaling through CaMKII-mediated Degradation of the SMRT Corepressor Protein

Serine-threonine Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is the key component in noncanonical Wnt5a signaling and has been shown to regulate its signaling. In this study, we found that CaMKII induced by Wnt5a remarkably reduced the protein stability of the silencing mediator of retino...

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Autores principales: Ann, Eun-Jung, Kim, Hwa-Young, Seo, Mi-Sun, Mo, Jung-Soon, Kim, Mi-Yeon, Yoon, Ji-Hye, Ahn, Ji-Seon, Park, Hee-Sae
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481284/
https://ncbi.nlm.nih.gov/pubmed/22888005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356048
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