Wnt5a Controls Notch1 Signaling through CaMKII-mediated Degradation of the SMRT Corepressor Protein

Serine-threonine Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is the key component in noncanonical Wnt5a signaling and has been shown to regulate its signaling. In this study, we found that CaMKII induced by Wnt5a remarkably reduced the protein stability of the silencing mediator of retino...

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Autors principals: Ann, Eun-Jung, Kim, Hwa-Young, Seo, Mi-Sun, Mo, Jung-Soon, Kim, Mi-Yeon, Yoon, Ji-Hye, Ahn, Ji-Seon, Park, Hee-Sae
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Protein Synthesis and Degradation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481284/
https://ncbi.nlm.nih.gov/pubmed/22888005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356048
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