Wnt5a Controls Notch1 Signaling through CaMKII-mediated Degradation of the SMRT Corepressor Protein

Serine-threonine Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is the key component in noncanonical Wnt5a signaling and has been shown to regulate its signaling. In this study, we found that CaMKII induced by Wnt5a remarkably reduced the protein stability of the silencing mediator of retino...

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Detalhes bibliográficos
Main Authors: Ann, Eun-Jung, Kim, Hwa-Young, Seo, Mi-Sun, Mo, Jung-Soon, Kim, Mi-Yeon, Yoon, Ji-Hye, Ahn, Ji-Seon, Park, Hee-Sae
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481284/
https://ncbi.nlm.nih.gov/pubmed/22888005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356048
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