Expression of functional alternative telomerase RNA component gene in mouse brain and in motor neurons cells protects from oxidative stress

Telomerase, a ribonucleoprotein, is highly expressed and active in many tumor cells and types, therefore it is considered to be a target for anti-cancer agents. On the other hand, recent studies demonstrated that activation of telomerase is a potential therapeutic target for age related diseases. Te...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Eitan, Erez, Tamar, Admoni, Yossi, Grin, Peleg, Refael, Braiman, Alex, Priel, Esther
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Research Paper: Gerotarget (Focus on Aging)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346639/
https://ncbi.nlm.nih.gov/pubmed/27823970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13049
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