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Telomerase increasing compound protects hippocampal neurons from amyloid beta toxicity by enhancing the expression of neurotrophins and plasticity related genes

The telomerase reverse transcriptase protein, TERT, is expressed in the adult brain and its exogenic expression protects neurons from oxidative stress and from the cytotoxicity of amyloid beta (Aβ). We previously showed that telomerase increasing compounds (AGS) protected neurons from oxidative stre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Baruch-Eliyahu, Natalie, Rud, Vladislav, Braiman, Alex, Priel, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889131/
https://ncbi.nlm.nih.gov/pubmed/31792359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54741-7
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