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Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis
Telomerase is expressed in the neonatal brain, in distinct regions of adult brain, and was shown to protect developing neurons from apoptosis. Telomerase reactivation by gene manipulation reverses neurodegeneration in aged telomerase-deficient mice. Hence, we and others hypothesized that increasing...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
WILEY-VCH Verlag
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376858/ https://ncbi.nlm.nih.gov/pubmed/22351600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200212 |
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