Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis

Telomerase is expressed in the neonatal brain, in distinct regions of adult brain, and was shown to protect developing neurons from apoptosis. Telomerase reactivation by gene manipulation reverses neurodegeneration in aged telomerase-deficient mice. Hence, we and others hypothesized that increasing...

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Bibliographic Details
Main Authors: Eitan, Erez, Tichon, Ailon, Gazit, Aviv, Gitler, Daniel, Slavin, Shimon, Priel, Esther
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376858/
https://ncbi.nlm.nih.gov/pubmed/22351600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200212
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