Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway

This study aims to investigate the effect of Endothelial-Monocyte-Activating Polypeptide-II (EMAP-II) combined with temozolomide (TMZ) upon glioblastoma stem cells (GSCs) and its possible molecular mechanisms. In this study, combination of EMAP-II with TMZ inhibited cell viability, migration and inv...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Zhou, Wei, Liu, Libo, Xue, Yixue, Zheng, Jian, Liu, Xiaobai, Ma, Jun, Li, Zhen, Liu, Yunhui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346543/
https://ncbi.nlm.nih.gov/pubmed/28348518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00068
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