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E3-Independent Constitutive Monoubiquitination Complements Histone Methyltransferase Activity of SETDB1
Ubiquitination typically occurs through the sequential action of three enzymes catalyzing ubiquitin activation (E1), conjugation (E2) and ligation (E3) and regulates diverse eukaryotic cellular processes. Although monoubiquitination commonly confers nondegradative activities, mechanisms underlying i...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5346476/ https://ncbi.nlm.nih.gov/pubmed/27237050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.04.022 |
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