Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

Disruption of the histone modification patterns is one of the most common features of human tumors. However, few genetic alterations in the histone modifier genes have been described in tumorigenesis. Herein we show that the histone methyltransferase SETDB1 undergoes gene amplification in non-small...

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Dades bibliogràfiques
Autors principals: Rodriguez-Paredes, M, Martinez de Paz, A, Simó-Riudalbas, L, Sayols, S, Moutinho, C, Moran, S, Villanueva, A, Vázquez-Cedeira, M, Lazo, P A, Carneiro, F, Moura, C S, Vieira, J, Teixeira, M R, Esteller, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031636/
https://ncbi.nlm.nih.gov/pubmed/23770855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.239
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