Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

Disruption of the histone modification patterns is one of the most common features of human tumors. However, few genetic alterations in the histone modifier genes have been described in tumorigenesis. Herein we show that the histone methyltransferase SETDB1 undergoes gene amplification in non-small...

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Detalhes bibliográficos
Main Authors: Rodriguez-Paredes, M, Martinez de Paz, A, Simó-Riudalbas, L, Sayols, S, Moutinho, C, Moran, S, Villanueva, A, Vázquez-Cedeira, M, Lazo, P A, Carneiro, F, Moura, C S, Vieira, J, Teixeira, M R, Esteller, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031636/
https://ncbi.nlm.nih.gov/pubmed/23770855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.239
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