Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

Disruption of the histone modification patterns is one of the most common features of human tumors. However, few genetic alterations in the histone modifier genes have been described in tumorigenesis. Herein we show that the histone methyltransferase SETDB1 undergoes gene amplification in non-small...

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Hlavní autoři: Rodriguez-Paredes, M, Martinez de Paz, A, Simó-Riudalbas, L, Sayols, S, Moutinho, C, Moran, S, Villanueva, A, Vázquez-Cedeira, M, Lazo, P A, Carneiro, F, Moura, C S, Vieira, J, Teixeira, M R, Esteller, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Short Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031636/
https://ncbi.nlm.nih.gov/pubmed/23770855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.239
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