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Non-canonical NFκB mutations reinforce pro-survival TNF response in multiple myeloma through an autoregulatory RelB:p50 NFκB pathway

Environmental drug resistance constitutes a serious impediment for therapeutic intervention in multiple myeloma. Tumor-promoting cytokines, such as tumor necrosis factor (TNF), induce nuclear factor-κB (NFκB)- driven expression of pro-survival factors, which confer resistance in myeloma cells to apo...

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Detaylı Bibliyografya
Yayımlandı:Oncogene
Asıl Yazarlar: Roy, P, Mukherjee, T, Chatterjee, B, Vijayaragavan, B, Banoth, B, Basak, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346295/
https://ncbi.nlm.nih.gov/pubmed/27641334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.309
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