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Integrated Regulation of Hepatic Lipid and Glucose Metabolism by ATGL and FoxO Proteins
FoxO proteins are major targets of insulin action. Adipose triacylglycerol (TAG) lipase mediates the first step in TAG hydrolysis and FoxO1 stimulates ATGL expression in adipose tissue. Here, we report that FoxO1 also stimulates ATGL and suppresses expression of its inhibitor, the G0/G1 switch gene...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5346032/ https://ncbi.nlm.nih.gov/pubmed/27050511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.021 |
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