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Integrated Regulation of Hepatic Lipid and Glucose Metabolism by ATGL and FoxO Proteins

FoxO proteins are major targets of insulin action. Adipose triacylglycerol (TAG) lipase mediates the first step in TAG hydrolysis and FoxO1 stimulates ATGL expression in adipose tissue. Here, we report that FoxO1 also stimulates ATGL and suppresses expression of its inhibitor, the G0/G1 switch gene...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Zhang, Wenwei, Bu, So Young, Mashek, Mara T., O-Sullivan, InSug, Sibai, Zakaria, Khan, Salmaan A., Ikayeva, Olga, Newgard, Christopher B., Mashek, Douglas G., Unterman, Terry G.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346032/
https://ncbi.nlm.nih.gov/pubmed/27050511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.021
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